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Your Guide to the Ultimate American BBQ

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The nights are drawing out, the mornings are getting brighter and many of us are looking forward to BBQ season. Getting everybody around to enjoy some homegrown produce and roast some delicious meat on the grill is a cause for celebration. If you’re a little anxious about making sure your BBQ is one to remember then we’ve got some tips that will ease any worries. Whether you want to make sure your vegan guests are catered for,
avoid burning the meat, or make sure there’s an ambience that will help everybody to relax and enjoy themselves, we’ve got you covered. So, if you’re ready to host the BBQ of the year, this is our guide.

Don’t Forget The Fruit Bowl

Nobody likes arriving to a BBQ and immediately having a plate of meat thrust at them, it’s far nicer to enjoy a few drinks and a chat before dinner starts in earnest. However, one tradition that we really need to get back into is having a fruit bowl, or platter laid out for guests to snack on whilst they mingle. Back in the day we appreciated fruits so much more, they were symbols of wealth and beauty, hence their use in the slot machines of
yesteryear, and even in the online slots of today. In some cultures, they’re still given as gifts and can fetch hundreds of thousands of dollars.

So, if you’ve had a bumper crop of raspberries, or you’ve got some beautiful peaches that need eating up, make a centerpiece of them.

Grazing platters are all the rage at the moment and they can make a selection of fruit look really special. You could poach the peaches in syrup and lay them on a bed of pillowy ricotta. Sprinkle over a few mint leaves, crushed pistachios, or plump raspberries and you’ve got an appetizing platter that looks elegant and tastes divine. One or two of these fruit boards will keep everybody happily munching and show off some of the fruits of your garden too.

Salads Are Important

We aren’t suggesting that your BBQ becomes a vegetarian affair, but a couple of nice salads will go a long way towards creating not only a healthier meal, but a more exciting one for your guests. Not to mention, meat is expensive, so your wallet will thank you for this tip too. If you’ve got any vegetarian guests coming then sticking some vegetable kebabs or halloumi on the grill will certainly be appreciated, but so too will making some
delicious salads.

Gone are the days of wilted iceberg with tomatoes and cucumber, instead, make something exciting. If you’ve got a herb garden then make use of the abundance of flavour by finely chopping up some herbs into a delicious tabbouleh. You could cook up and cool some grains like quinoa, lentils, or bulgur wheat and use that as a hearty base for a vegetable packed salad. A mandolin can make short work of julienneing vegetables, which
adds great texture and colour to your starchy base. Spike your salads with crumbly feta cheese, or some citrus fruit zest and you’ll be hard pressed to get a look in when your guests get a taste.

Patience is a Virtue

With the non-meat catering out of the way, it’s time to turn your attention to the grill. The biggest and most common mistake that people make is putting the meat on the grill too early. Set the grill going way before guests arrive and leave it to smoulder until the coals are white hot. Only once the flames have died right back should you put the meat on the BBQ. Before you pop them on the grill, make sure that the bars are greased, this will save
your burgers from sticking and make flipping a breeze.

As for the meat you serve, the choice is entirely yours. Our suggestion is to opt for no more than three or maybe four different types of meat, as each of them will require a different method of cooking which takes up time that you could be spending with your guests. Everybody loves burgers, sausages and a piece of perfectly charred chicken, so keep the crowds happy and stick to those. By sticking to just three cuts, you’ll be able to cook them all perfectly, instead of making a half-hearted attempt at six or seven.

Arrange a Playlist

Finally, if you’re a little concerned about getting the party atmosphere started then putting a playlist on will help things get going. There are a surprising number of really good playlists that are already made for you on Spotify, so you can simply type in the mood that you’d like and scroll through the options.

Alternatively, you can choose to share your playlists with guests and ask them to add the songs that they would like to hear. That way, everyone has got a conversation starter as they try to find out who picked which songs and why. Have fun with this bit, after all, that’s what a good BBQ is all about.

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How to Streamline Your Car Sales in Toronto? The Pointer for Car Sellers

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Many car owners doubt whether selling their property is worth the hassle they may face during sales. That’s reasonable because a car is not a small item, and you probably spent much on its purchase at some point and regularly invested in it to maintain it in good condition. Then, selling it for pennies is not your choice.

We went ahead and contacted Topcashforcars.ca, a company that is reputed for giving the highest cash prices for cars in Toronto. Their approach is straightforward and reduces hassle for sellers who want to sell their vehicles profitably without the complexities of dealing with customers.

Choosing the Right Counterparty Is a Key to Success

First, have you already decided where and to whom you can sell a vehicle? That’s your #1 thing to do. Typically, the choice is either selling autos to individuals who want to buy a second-market car to save some dollars or to specialized companies engaged in car buying. These companies are diverse enough and they often offer good conditions for a seller although their pricing is diverse too.

How can you get in touch with such buyers?

  • For individuals who buy second-hand vehicles, you can search on big Canadian bulletin boards online and sometimes, on social networks.
  • For the companies to deal with, Google is your best friend to ask for help. However, our consultants, Topcashforcars.ca also are among these buyers, so you can make it even easier and apply to them.

What is more beneficial for a car seller at this stage? We can surely say that dealing with car-buying companies considerably saves you time. The whole negotiation process can take a couple of hours, so you won’t wait long and remain under pressure of uncertainty. 

Making It Lighting-Fast Is Possible

The previous tip leads to another one: you can sell a car in a lighting-fast mode. Just do some easy preps like its examination at the service station to consider what price can you claim for it and clean it up. This takes no more than a day if you have a good service station in your neighborhood and it helps clearly understand the price and the condition of your car.

Then, you can ensure you set a real price by using special online calculators provided by the same car-buying companies. It may take just a couple of minutes and you’ll get a precise calculation based on your vehicle’s type, age, model, condition, and specific features. 

Getting Cash Instead of Bank Transfers or Checks Is Faster

One more thing you can do to sell your auto as fast as possible is to sell it for cash. Bank operations often take additional days to be processed. Thus, even if you are lucky enough to get in touch with a good buyer quickly, and even if you conclude a deal in a day or two, it’s not guaranteed that you get money to your bank account similarly quickly. Applying for cash transactions you avoid troubles with banks and extra commissions for the transaction too.

As you can see, selling a vehicle can be eating pears for you if you plan your sale and follow the tips we shared in this article.

If followed, these recommendations can allow you to easily sell your car and make a handsome return in the process. It is even more rewarding because time and energy has become invaluable and cash for cars, Toronto based companies and specifically Topcashforcars.ca, will ensure the vehicle is sold for the best price with little input from the owner. When selling a car, it is ideal to do enough research, plan and choose the right buyers so that the car selling process is fast and efficient.

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New frontiers in prostate cancer treatment with Actinium-225

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Prostate cancer is one of the most widespread malignant tumors in men. The pathology is successfully
treated in the first three stages, when the tumor can be removed or destroyed by radiation, but the disease at the metastatic stage becomes incurable. Surgery is usually not performed in such patients, and the main methods of treatment are hormonal and chemotherapy.

At a certain point this treatment stops working. 177Lu-PSMA-617 – Lutetium radiotargeted therapy,
becomes the next stage of treatment. A less common method of radiotargeted therapy is the treatment of prostate cancer with Actinium-225. It allows for a good outcome even in patients who have not responded to Lutetium therapy. In addition, the possibility of combined use of Actinium and Lutetium as part of tandem therapy is being investigated.

Principle of the method

Prostate cancer cells express a protein called prostate-specific membrane antigen (PSMA), which is not found in other tissues. PSMA is a target for the radiopharmaceutical. Once injected into the body, the drug accumulates only in tissues with high levels of PSMA because it binds to this protein. This results in a selective effect on the tumor and its metastases with minimal side effects.

Various radionuclides can be attached to ligands that target PSMA. The first such radionuclide was
Lutetium-177, which was synthesized in Germany in 2010, and its efficacy was first confirmed in trials in 2015. The good results were subsequently confirmed in a large study involving 13 university hospitals in Germany.

In recent years, Actinium-225 has been used instead of Lutetium. It destroys cancer cells with alpha
radiation.

Advantages and disadvantages of Actinium-225

Lutetium-177 is still considered the mainstay of radiotargeted therapy for castration-resistant prostate
cancer. However, Actinium is also used in certain situations, usually in patients with advanced cancer who have not responded to Lutetium treatment or when the efficacy of 177Lu-PSMA-617 has decreased after several courses (cancer progression has resumed).

Advantages of Actinium-225 over Lutetium-177:

● More pronounced effect due to alpha radiation causing double-strand breaks in DNA strands
● Less toxic effect on bone marrow and hematopoietic function due to shorter recovery time
● Works even in cases where the cancer is progressing against the background of Lutetium therapy

However, it is worth considering the disadvantages of this method:

● Limited evidence base compared to Lutetium
● Higher incidence of side effects, especially dry mouth

Who is a candidate for Actinium therapy

Radiotargeted therapy with Actinium is considered a novel treatment. The technique is indicated for
patients with metastatic castration-resistant prostate cancer (MCRPC) who:

● Have received Lutetium radiotargeted therapy but have not responded to it
● Have responded to Lutetium radiotargeted therapy, but have stopped responding after several
courses of treatment
● As part of tandem therapy: when Actinium and Lutetium are used in reduced doses

In summary, Actinium therapy is one of the last treatment options. It is used when chemotherapy, hormone therapy, radiotargeted therapy with Lutetium, and possibly targeted therapy (in the case of BRCA mutations, which occur in 28% of patients with metastatic prostate cancer) have already been tried. In addition, the choice of treatment tactics takes into account the location of the metastases. In the presence of predominantly bone metastases and pain syndrome, radionuclide therapy with Radium-223 is preferred, and in the presence of predominantly organ metastases, radiotargeted therapy with Lutetium or Actinium is performed.

If you want to undergo innovative treatment in Germany, visit Booking Health website. Our team will find a clinic for you and organize your trip.

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