Brownstone Institute
BMJ Exposes Scientific American’s Editor-in-Chief
From the Brownstone Institute
BY
In a shot across the bow against Scientific American’s continued descent into unscientific twaddle, a BMJ investigation documented over a dozen social media posts by editor-in-chief Laura Helmuth promoting transgender care for children, despite scientific evidence showing such treatment has had “devastating consequences” for minors.
“Laws preventing trans kids from getting gender-affirming treatment are dangerous and abusive, as well as against all medical evidence,” Helmuth posted on X in late 2022, one of many examples that the BMJ sent to Scientific American and its publisher Springer Nature, asking them to explain Helmuth’s trans advocacy which runs contrary to medical evidence.
In other social media posts, Helmuth has labeled critics of dangerous transgender medicine for children “biased,” “bigoted,” “antiscience,” “misinformation,” “cruel,” and compared them to Nazis.
Last year, Helmut promoted false news in Scientific American that argued, “The research is clear and all the relevant medical organizations agree: Gender-affirming care is evidence-based & medically necessary & leads to much better outcomes for trans kids than refusing them care.”
Six days later, the BMJ released an investigation of new research finding that the evidence for transgender care for children lacked evidence and that medical authorities were urging caution.

England, Scotland, Wales, and Sweden have all ceased prescribing puberty blockers for children, except for research studies, and the Finnish psychiatrist who first founded the field of transgender care for children now calls it “dangerous.” Many countries’ medical authorities have concluded that studies promoting trans treatment for children were either biased or of low quality.
The BMJ’s targeting of Laura Helmuth was a warning, of sorts—an admonition that Helmuth should focus on science, cease the advocacy, and stop saying stupid things. But if you continue to read Scientific American, expect Helmuth to continue saying stupid things.
Last month, Harvard’s Steven Pinker labeled Helmuth a “woke fanatic” on X and promoted an article discussing Scientific American’s descent into progressive ideology. “Another noble American institution run into the ground when clueless trustees handed over the keys to a woke fanatic,” Pinker posted.

The article Pinker promoted appeared in City Journal (“Unscientific American”) and carefully documented the magazine’s decline into a political rag since Helmuth took the reins in early 2020. Other outlets have also cast a disapproving eye on Helmuth’s political crusades.
The Wall Street Journal noted that Helmuth tweeted last year that “sparrows have four different chromosomally distinct sexes,” forcing the community notes on X to correct Helmuth’s error.
“It’s just incredible how far @sciam — a periodical I admired — has fallen from its mission to provide accurate, clear, and vivid coverage of science,” Yale professor and physician Nicholas Christakis, posted on X.
“EXCLUSIVE: unScientific American! Popular magazine is slammed by experts over ‘woke’ article titled ‘Why Human Sex is Not Binary’,” reported the Daily Mail, a few months prior to Christakis’ criticism of Helmuth. Dr Carole Hooven, an evolutionary biologist at Harvard University, told the Daily Mail that Scientific American’s unscientific claims could put women in danger.
“On average, men are bigger and stronger than women, and commit the overwhelming majority of rapes and murders. Most men could kill most women with their bare hands,” Hooven explained. “These facts have informed the establishment of laws and social policies that protect female spaces, particularly those where women are in vulnerable positions such as where they sleep or shower (prison cells and locker rooms, for example).”
Chicago University emeritus professor of ecology and evolution, Jerry Coyne, has written several times about Helmuth promoting factually inaccurate claims in Scientific American, which he labeled “Scientific Pravda.”
Somebody called my attention to three new articles and op-eds in Scientific American that have no science in them, but are pure ideology of the “progressive” sort. I agree with some of the sentiments expressed in them, as in the first one. But my point is, as usual, to show how everything in science, including its most widely-read “popular” magazine, is being taken over by ideology. Not only that, but it’s ideology of only one stripe: Leftist “progressive” (or “woke,” if you will) ideology, so that the “opinion” section is not a panoply of divergent views, but gives only one view, like a Scientific Pravda. Remember that the editor refused when I offered to write an op-ed expressing different (but of course not right-wing) views.
In a previous City Journal article in 2022, science writer Nicholas Wade called Scientific American’s shift away from science a “new Lysenkoism” referring to the Soviet doctrine that forced biologists to ignore evolution and the genetics of plants to conform to political ideology.
And in an investigation I conducted for the BMJ (“The covid-19 lab leak hypothesis: did the media fall victim to a misinformation campaign?”) I noted that Helmuth harassed CDC Director Robert Redfield for telling CNN he thought the Covid virus may have come from a Wuhan lab:
The growing tendency to treat the lab leak scenario as worthy of serious investigation has put some reporters on the defensive. After Robert Redfield, former director of the Centers for Disease Control and Prevention, appeared on CNN in March, Scientific American’s editor in chief, Laura Helmuth, tweeted, “On CNN, former CDC director Robert Redfield shared the conspiracy theory that the virus came from the Wuhan lab.” The following day, Scientific American ran an essay calling the lab leak theory “evidence free.”
In short, Helmuth is a political fanatic who doesn’t care much for science, unless it’s science that fits her personal politics.
The BMJ’s investigation highlighted the Cass Review which found little evidence to support Helmuth’s claims that the puberty blockers or other trans therapy for children are safe, including surgery. Dr. Hilary Cass is a British physician and former president of the Royal College of Paediatrics and Child Health, who spent three years examining the evidence for treating gender-questioning young people.
In a recent interview with the New York Times, Dr. Cass said that doctors in the United States are “out of date” with understanding trans care for children. “But what some organizations are doing is doubling down on saying the evidence is good,” Dr. Cass told the New York Times. “And I think that’s where you’re misleading the public.”
And in podcast for the BMJ, Dr. Cass noted that of the 100 studies for puberty blockers and hormone treatment, only two were of passable quality. She also dismissed claims by activists such as Helmuth that trans care lowers risk of suicide in children.
“There, unfortunately, is not evidence that gender affirming treatment in its broadest sense reduces the suicide risk,” Dr. Cass said, during the BMJ podcast.
Below are several social media posts by Laura Helmuth crusading for trans care for kids—many of them dangerous messages for children, all lacking quality medical evidence.


















To find the latest quality medical evidence on trans care for children, please read The Cass Review, which NHS England commissioned to improve NHS gender identity services, and ensure that children and young people who are questioning their gender identity or experiencing gender dysphoria receive a high standard of care, that meets their needs, is safe, holistic, and effective.
Republished from the author’s Substack
Brownstone Institute
Bizarre Decisions about Nicotine Pouches Lead to the Wrong Products on Shelves
From the Brownstone Institute
A walk through a dozen convenience stores in Montgomery County, Pennsylvania, says a lot about how US nicotine policy actually works. Only about one in eight nicotine-pouch products for sale is legal. The rest are unauthorized—but they’re not all the same. Some are brightly branded, with uncertain ingredients, not approved by any Western regulator, and clearly aimed at impulse buyers. Others—like Sweden’s NOAT—are the opposite: muted, well-made, adult-oriented, and already approved for sale in Europe.
Yet in the United States, NOAT has been told to stop selling. In September 2025, the Food and Drug Administration (FDA) issued the company a warning letter for offering nicotine pouches without marketing authorization. That might make sense if the products were dangerous, but they appear to be among the safest on the market: mild flavors, low nicotine levels, and recyclable paper packaging. In Europe, regulators consider them acceptable. In America, they’re banned. The decision looks, at best, strange—and possibly arbitrary.
What the Market Shows
My October 2025 audit was straightforward. I visited twelve stores and recorded every distinct pouch product visible for sale at the counter. If the item matched one of the twenty ZYN products that the FDA authorized in January, it was counted as legal. Everything else was counted as illegal.
Two of the stores told me they had recently received FDA letters and had already removed most illegal stock. The other ten stores were still dominated by unauthorized products—more than 93 percent of what was on display. Across all twelve locations, about 12 percent of products were legal ZYN, and about 88 percent were not.
The illegal share wasn’t uniform. Many of the unauthorized products were clearly high-nicotine imports with flashy names like Loop, Velo, and Zimo. These products may be fine, but some are probably high in contaminants, and a few often with very high nicotine levels. Others were subdued, plainly meant for adult users. NOAT was a good example of that second group: simple packaging, oat-based filler, restrained flavoring, and branding that makes no effort to look “cool.” It’s the kind of product any regulator serious about harm reduction would welcome.
Enforcement Works
To the FDA’s credit, enforcement does make a difference. The two stores that received official letters quickly pulled their illegal stock. That mirrors the agency’s broader efforts this year: new import alerts to detain unauthorized tobacco products at the border (see also Import Alert 98-06), and hundreds of warning letters to retailers, importers, and distributors.
But effective enforcement can’t solve a supply problem. The list of legal nicotine-pouch products is still extremely short—only a narrow range of ZYN items. Adults who want more variety, or stores that want to meet that demand, inevitably turn to gray-market suppliers. The more limited the legal catalog, the more the illegal market thrives.
Why the NOAT Decision Appears Bizarre
The FDA’s own actions make the situation hard to explain. In January 2025, it authorized twenty ZYN products after finding that they contained far fewer harmful chemicals than cigarettes and could help adult smokers switch. That was progress. But nine months later, the FDA has approved nothing else—while sending a warning letter to NOAT, arguably the least youth-oriented pouch line in the world.
The outcome is bad for legal sellers and public health. ZYN is legal; a handful of clearly risky, high-nicotine imports continue to circulate; and a mild, adult-market brand that meets European safety and labeling rules is banned. Officially, NOAT’s problem is procedural—it lacks a marketing order. But in practical terms, the FDA is punishing the very design choices it claims to value: simplicity, low appeal to minors, and clean ingredients.
This approach also ignores the differences in actual risk. Studies consistently show that nicotine pouches have far fewer toxins than cigarettes and far less variability than many vapes. The biggest pouch concerns are uneven nicotine levels and occasional traces of tobacco-specific nitrosamines, depending on manufacturing quality. The serious contamination issues—heavy metals and inconsistent dosage—belong mostly to disposable vapes, particularly the flood of unregulated imports from China. Treating all “unauthorized” products as equally bad blurs those distinctions and undermines proportional enforcement.
A Better Balance: Enforce Upstream, Widen the Legal Path
My small Montgomery County survey suggests a simple formula for improvement.
First, keep enforcement targeted and focused on suppliers, not just clerks. Warning letters clearly change behavior at the store level, but the biggest impact will come from auditing distributors and importers, and stopping bad shipments before they reach retail shelves.
Second, make compliance easy. A single-page list of authorized nicotine-pouch products—currently the twenty approved ZYN items—should be posted in every store and attached to distributor invoices. Point-of-sale systems can block barcodes for anything not on the list, and retailers could affirm, once a year, that they stock only approved items.
Third, widen the legal lane. The FDA launched a pilot program in September 2025 to speed review of new pouch applications. That program should spell out exactly what evidence is needed—chemical data, toxicology, nicotine release rates, and behavioral studies—and make timely decisions. If products like NOAT meet those standards, they should be authorized quickly. Legal competition among adult-oriented brands will crowd out the sketchy imports far faster than enforcement alone.
The Bottom Line
Enforcement matters, and the data show it works—where it happens. But the legal market is too narrow to protect consumers or encourage innovation. The current regime leaves a few ZYN products as lonely legal islands in a sea of gray-market pouches that range from sensible to reckless.
The FDA’s treatment of NOAT stands out as a case study in inconsistency: a quiet, adult-focused brand approved in Europe yet effectively banned in the US, while flashier and riskier options continue to slip through. That’s not a public-health victory; it’s a missed opportunity.
If the goal is to help adult smokers move to lower-risk products while keeping youth use low, the path forward is clear: enforce smartly, make compliance easy, and give good products a fair shot. Right now, we’re doing the first part well—but failing at the second and third. It’s time to fix that.
Addictions
The War on Commonsense Nicotine Regulation
From the Brownstone Institute
Cigarettes kill nearly half a million Americans each year. Everyone knows it, including the Food and Drug Administration. Yet while the most lethal nicotine product remains on sale in every gas station, the FDA continues to block or delay far safer alternatives.
Nicotine pouches—small, smokeless packets tucked under the lip—deliver nicotine without burning tobacco. They eliminate the tar, carbon monoxide, and carcinogens that make cigarettes so deadly. The logic of harm reduction couldn’t be clearer: if smokers can get nicotine without smoke, millions of lives could be saved.
Sweden has already proven the point. Through widespread use of snus and nicotine pouches, the country has cut daily smoking to about 5 percent, the lowest rate in Europe. Lung-cancer deaths are less than half the continental average. This “Swedish Experience” shows that when adults are given safer options, they switch voluntarily—no prohibition required.
In the United States, however, the FDA’s tobacco division has turned this logic on its head. Since Congress gave it sweeping authority in 2009, the agency has demanded that every new product undergo a Premarket Tobacco Product Application, or PMTA, proving it is “appropriate for the protection of public health.” That sounds reasonable until you see how the process works.
Manufacturers must spend millions on speculative modeling about how their products might affect every segment of society—smokers, nonsmokers, youth, and future generations—before they can even reach the market. Unsurprisingly, almost all PMTAs have been denied or shelved. Reduced-risk products sit in limbo while Marlboros and Newports remain untouched.
Only this January did the agency relent slightly, authorizing 20 ZYN nicotine-pouch products made by Swedish Match, now owned by Philip Morris. The FDA admitted the obvious: “The data show that these specific products are appropriate for the protection of public health.” The toxic-chemical levels were far lower than in cigarettes, and adult smokers were more likely to switch than teens were to start.
The decision should have been a turning point. Instead, it exposed the double standard. Other pouch makers—especially smaller firms from Sweden and the US, such as NOAT—remain locked out of the legal market even when their products meet the same technical standards.
The FDA’s inaction has created a black market dominated by unregulated imports, many from China. According to my own research, roughly 85 percent of pouches now sold in convenience stores are technically illegal.
The agency claims that this heavy-handed approach protects kids. But youth pouch use in the US remains very low—about 1.5 percent of high-school students according to the latest National Youth Tobacco Survey—while nearly 30 million American adults still smoke. Denying safer products to millions of addicted adults because a tiny fraction of teens might experiment is the opposite of public-health logic.
There’s a better path. The FDA should base its decisions on science, not fear. If a product dramatically reduces exposure to harmful chemicals, meets strict packaging and marketing standards, and enforces Tobacco 21 age verification, it should be allowed on the market. Population-level effects can be monitored afterward through real-world data on switching and youth use. That’s how drug and vaccine regulation already works.
Sweden’s evidence shows the results of a pragmatic approach: a near-smoke-free society achieved through consumer choice, not coercion. The FDA’s own approval of ZYN proves that such products can meet its legal standard for protecting public health. The next step is consistency—apply the same rules to everyone.
Combustion, not nicotine, is the killer. Until the FDA acts on that simple truth, it will keep protecting the cigarette industry it was supposed to regulate.
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