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Brownstone Institute

Pfizer Lied to Us Again

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12 minute read

From Brownstone Institute

BY Ian MillerIAN MILLER 

There used to be a time where claims from pharmaceutical companies may have been treated with some degree of skepticism from major institutions and media outlets.

Yet in late 2020 and into 2021, suddenly skepticism turned to complete blind faith. But what changed? Why, political incentives, of course!

Initially, Covid vaccines produced by Pfizer were seen as dangerous and untested; they were considered a Trump vaccine that only idiots who were willing to risk their own health would take. However when the 2020 election had been officially decided, and Biden and his political allies represented the Covid vaccines as the pathway out of the pandemic, a moral choice that would help yourself and others, narratives and incentives changed dramatically.

Pfizer became a heroic symbol of virtue, and all questioning of Covid vaccines was grounds for immediate expulsion from polite society, regardless of the actual efficacy of Pfizer’s products.

Much of the blame for the vaccines’ underperformance could be placed on Pfizer itself; the company relentlessly promoted hopelessly inaccurate efficacy estimates and supported efforts to unnecessarily mandate mRNA shots.

Sure enough, on the back of progressive orthodoxy, corporate and institutional incompetence and media activism, they proudly reported record revenues.

We all know how that turned out in 2022 and 2023.

Skepticism towards Pfizer’s vaccine was obviously quite well warranted. And it turns out that now we, and of course, Pfizer’s chief promoters in the media and public health class should have been even more skeptical.

They weren’t.

Pfizer’s Claims On Covid Treatments Were Wildly Inaccurate

As the Covid vaccines failed spectacularly to stop the spread of infections and did nothing to lessen all-cause mortality or even decrease population level Covid-associated deaths in highly vaccinated countries, Pfizer saw another opportunity.

Sure, their signature product failed to perform as expected. So why not create another one as an antidote?

Enter Paxlovid.

Paxlovid, an antiviral drug, was supposed to help individuals with symptomatic Covid, who’d already been infected, recover more quickly and lessen the risk of severe illness. Sounds great right?

It would appear that it sure did to Anthony Fauci and the cadre of media-promoted “experts.”

Fauci praised Paxlovid in 2022, after the mRNA vaccines and booster doses failed to prevent him from contracting Covid. Bizarrely, Fauci implied that the same Pfizer products that he demanded everyone take would not have been enough to keep him healthy, saying that he believed Paxlovid had kept him out of the hospital.

Never mind, of course, that Fauci had a “rebound” case of Covid-19 after taking Paxlovid and getting vaccinated and boosted. Acknowledging imperfections would undercut his desire to get everyone to take more of his preferred products.

Paxlovid made headlines again later in 2022 as Rochelle Walensky also praised Pfizer’s efforts, despite once again testing positive for “rebound” Covid after Paxlovid treatments.

Even today, the CDC’s own website says Paxlovid is an “effective” treatment for those who’ve contracted the virus and want to avoid severe illness.

There’s just one problem; it’s not true.

A newly released study on Paxlovid on randomized adults with symptomatic Covid; one subset was given Paxlovid (nirmatrelvir-ritonavir) or a placebo every 12 hours for five days, with the intent of determining how effective it was at “sustained alleviation” of Covid-19 symptoms.

In this phase 2–3 trial, we randomly assigned adults who had confirmed Covid-19 with symptom onset within the past 5 days in a 1:1 ratio to receive nirmatrelvir–ritonavir or placebo every 12 hours for 5 days. Patients who were fully vaccinated against Covid-19 and who had at least one risk factor for severe disease, as well as patients without such risk factors who had never been vaccinated against Covid-19 or had not been vaccinated within the previous year, were eligible for participation. Participants logged the presence and severity of prespecified Covid-19 signs and symptoms daily from day 1 through day 28. The primary end point was the time to sustained alleviation of all targeted Covid-19 signs and symptoms. Covid-19–related hospitalization and death from any cause were also assessed through day 28.

Spoiler alert: it wasn’t effective at all.

Their measured results revealed that there was effectively no difference whatsoever in the “sustained alleviation” of symptoms between Paxlovid and a placebo. Those taking Pfizer’s miracle antiviral treatment saw their “signs and symptoms” resolve after 12 days, while the placebo recipients took 13 days.

The median time to sustained alleviation of all targeted signs and symptoms of Covid-19 was 12 days in the nirmatrelvir–ritonavir group and 13 days in the placebo group (P=0.60). Five participants (0.8%) in the nirmatrelvir–ritonavir group and 10 (1.6%) in the placebo group were hospitalized for Covid-19 or died from any cause (difference, −0.8 percentage points; 95% confidence interval, −2.0 to 0.4).

This is the product that to this day is relentlessly promoted by the CDC, the media, and politicians as an effective tool to reduce the severity of symptoms and the length of illness. And it was virtually meaningless.

Even with regards to the most severe outcomes, hospitalization, and death, the difference was negligible. Confidence intervals for the difference in outcome even stretched to a positive relationship, meaning that it’s within the bounds of possibility that more people died or were hospitalized after taking Paxlovid than a placebo.

Succinctly, the researchers confirmed in their summary that there was no difference between the two treatments.

The time to sustained alleviation of all signs and symptoms of Covid-19 did not differ significantly between participants who received nirmatrelvir–ritonavir and those who received placebo.

But who are these researchers, you might ask…surely they’re fringe scientists, desperate to undercut a big, bad pharmaceutical company, right? How else could their conclusions so thoroughly undermine Pfizer?

Let’s take a look at the disclosure to see who funded this study, designed the trial, conducted it, collected the data, and analyzed the results. Surely, that will reveal the nefarious intentions behind this dastardly attempt to cut at the heart of Pfizer’s miracle drug.

Pfizer was responsible for the trial design and conduct and for data collection, analysis, and interpretation. The first draft of the manuscript was written by medical writers (funded by Pfizer) under direction from the authors.

Oh. Oh no.

Pfizer created the trial, conducted it, collected the data, and analyzed it. And it found that Paxlovid made no difference to the resolution of symptoms or with keeping people alive or out of the hospital. That has to sting.

Even worse, Covid vaccination was once again proven to be almost entirely irrelevant where results were concerned. Results were the same between “high-risk subgroups,” meaning those who had been vaccinated but had an elevated risk for more serious symptoms, and those who had never been vaccinated or had received the last dose more than a year ago.

Similar results were observed in the high-risk subgroup (i.e., participants who had been vaccinated and had at least one risk factor for severe illness) and in the standard-risk subgroup (i.e., those who had no risk factors for severe illness and had never been vaccinated or had not been vaccinated within the previous 12 months).

So not only did Paxlovid not make a difference, but vaccination status AND Paxlovid wasn’t enough to create a sizable gap in outcomes between healthy, unvaccinated individuals.

But wait, there’s more.

Viral load rebounds were also more common in the Paxlovid group, and symptom and viral load rebounds combined were more common among those taking Pfizer’s treatment. While percentages were generally low, other studies have pegged Paxlovid-associated rebound as occurring nearly one quarter of the time.

So it’s not particularly effective at reducing symptoms or resolving them more quickly, doesn’t lead to statistically significant improvements in the most severe outcomes, and is more likely to result in a rebound case of the illness it’s supposed to be protecting you from.

Sounds exactly like the type of product that Fauci, Walensky, and the CDC would praise, doesn’t it?

Paxlovid is the entire Covid-pharmaceutical complex summarized perfectly. Created to solve a problem that was supposed to be fixed by another product…understudied, overhyped by the “experts,” and prematurely authorized by a desperate FDA…and ultimately shown to be mostly ineffective.

Once again, the actual science disproves The Science™. And once again, we’ll get no acknowledgment of it or apologies for the billions of taxpayer dollars wasted. Can’t wait to see what Pfizer does for an encore.

Republished from the author’s Substack

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Brownstone Institute

The Deplorable Ethics of a Preemptive Pardon for Fauci

Published on

From the Brownstone Institute

By Alex Washburne 

Anthony “I represent science” Fauci can now stand beside Richard “I am not a crook” Nixon in the history books as someone who received the poison pill of a preemptive pardon.

While Nixon was pardoned for specific charges related to Watergate, the exact crimes for which Fauci was pardoned are not specified. Rather, the pardon specifies:

Baseless and politically motivated investigations wreak havoc on the lives, safety, and financial security of targeted individuals and their families. Even when individuals have done nothing wrong – and in fact have done the right things – and will ultimately be exonerated, the mere fact of being investigated and prosecuted can irreparably damage reputations and finances.

In other words, the dying breath of the Biden administration appears to be pardoning Fauci for crimes he didn’t commit, which would seem to make a pardon null and void. The pardon goes further than simply granting clemency for crimes. Clemency usually alleviates the punishment associated with a crime, but here Biden attempts to alleviate the burden of investigations and prosecutions, the likes of which our justice system uses to uncover crimes.

It’s one thing to pardon someone who has been subjected to a fair trial and convicted, to say they have already paid their dues. Gerald Ford, in his pardon of Richard Nixon, admitted that Nixon had already paid the high cost of resigning from the highest office in the land. Nixon’s resignation came as the final chapter of prolonged investigations into his illegal and unpresidential conduct during Watergate, and those investigations provided us the truth we needed to know that Nixon was a crook and move on content that his ignominious reputation was carve d into stone for all of history.

Fauci, meanwhile, has evaded investigations on matters far more serious than Watergate. In 2017, DARPA organized a grant call – the PREEMPT call – aiming to preempt pathogen spillover from wildlife to people. In 2018 a newly formed collaborative group of scientists from the US, Singapore, and Wuhan wrote a grant – the DEFUSE grant – proposing to modify a bat sarbecovirus in Wuhan in a very unusual way. DARPA did not fund the team because their work was too risky for the Department of Defense, but in 2019 Fauci’s NIAID funded this exact set of scientists who never wrote a paper together prior or since. In late 2019, SARS-CoV-2 emerged in Wuhan with the precise modifications proposed in the DEFUSE grant submitted to PREEMPT.

It’s reasonable to be concerned that this line of research funded by Fauci’s NIAID may have caused the pandemic. In fact, if we’re sharp-penciled and honest with our probabilities, it’s likely beyond reasonable doubt that SARS-CoV-2 emerged as a consequence of research proposed in DEFUSE. What we don’t know, however, is whether the research proceeded with US involvement or not.

Congress used its constitutionally-granted investigation and oversight responsibilities to investigate and oversee NIAID in search of answers. In the process of these investigations, they found endless pages of emails with unjustified redactions, evidence that Fauci’s FOIA lady could “make emails disappear,” Fauci’s right-hand-man David Morens aided the DEFUSE authors as they navigated disciplinary measures at NIH and NIAID, and there were significant concerns that NIAID sought to obstruct investigations and destroy federal records.

Such obstructive actions did not inspire confidence in the innocence of Anthony Fauci or the US scientists he funded in 2019. On the contrary, Fauci testified twice under oath saying NIAID did not fund gain-of-function research of concern in Wuhan…but then we discovered a 2018 progress report of research NIAID funded in Wuhan revealing research they funded had enhanced the transmissibility of a bat SARS-related coronavirus 10,000 times higher than the wild virus. That is, indisputably, gain-of-function research of concern. Fauci thus lied to the American public and perjured himself in his testimony to Congress, and Senator Rand Paul (R-KY) has referred Fauci’s perjury charges to the Department of Justice.

What was NIAID trying to preempt with their obstruction of Congressional investigations? What is Biden trying to preempt with his pardon of Fauci? Why do we not have the 2019 NIAID progress report from the PI’s who submitted DEFUSE to PREEMPT and later received funding from NIAID?

It is deplorable for Biden to preemptively pardon Fauci on his last day in office, with so little known about the research NIAID funded in 2019 and voters so clearly eager to learn more. With Nixon’s preemptive pardon, the truth of his wrongdoing was known and all that was left was punishment. With Fauci’s preemptive pardon, the truth is not yet known, NIAID officials in Fauci’s orbit violated federal records laws in their effort to avoid the truth from being known, and Biden didn’t preemptively pardon Fauci to grant clemency and alleviate punishment, but to stop investigations and prosecutions the likes of which could uncover the truth.

I’m not a Constitutional scholar prepared to argue the legality of this maneuver, but I am an ethical human being, a scientist who contributed another grant to the PREEMPT call, and a scientist who helped uncover some of the evidence consistent with a lab origin and quantify the likelihood of a lab origin from research proposed in the DEFUSE grant. Any ethical human being knows that we need to know what caused the pandemic, and to deprive the citizenry of such information from open investigations of NIAID research in 2019 would be to deprive us of critical information we need to self-govern and elect people who manage scientific risks in ways we see fit. As a scientist, there are critical questions about bioattribution that require testing, and the way to test our hypotheses is to uncover the redacted and withheld documents from Fauci’s NIAID in 2019.

The Biden administration’s dying breath was to pardon Anthony Fauci not for the convictions for crimes he didn’t commit (?) but to avoid investigations that could be a reputational and financial burden for Anthony Fauci. A pardon to preempt an investigation is not a pardon; it is obstruction. The Biden administration’s dying breath is to obstruct our pursuit of truth and reconciliation on the ultimate cause of 1 million Americans’ dying breaths.

To remind everyone what we still need to know, it helps to look through the peephole of what we’ve already found to inspire curiosity about what else we’d find if only the peephole could be widened. Below is one of the precious few emails investigative journalists pursuing FOIAs against NIAID have managed to obtain from the critical period when SARS-CoV-2 is believed to have emerged. The email connects DEFUSE PI’s Peter Daszak (EcoHealth Alliance), Ralph Baric (UNC), Linfa Wang (Duke-NUS), Ben Hu (Wuhan Institute of Virology), Shi ZhengLi (Wuhan Institute of Virology) and others in October 2019. The subject line “NIAID SARS-CoV Call – October 30/31” connects these authors to NIAID.

It is approximately in that time range – October/November 2019 – when SARS-CoV-2 is hypothesized to have entered the human population in Wuhan. When it emerged, SARS-CoV-2 was unique among sarbecoviruses in having a furin cleavage site, as proposed by these authors in their 2019 DEFUSE grant. Of all the places the furin cleavage site could be, the furin cleavage site of SARS-CoV-2 was in the S1/S2 junction of the Spike protein, precisely as proposed by these authors.

In order to insert a furin cleavage site in a SARS-CoV, however, the researchers would’ve needed to build a reverse genetic system, i.e. a DNA copy of the virus. SARS-CoV-2 is unique among coronaviruses in having exactly the fingerprint we would expect from reverse genetic systems. There is an unusual even spacing in the cutting/pasting sites for the enzymes BsaI and BsmBI and an anomalous hot-spot of silent mutations in precisely these sites, exactly as researchers at the Wuhan Institute of Virology have done for other coronavirus reverse genetic systems. The odds of such an extreme synthetic-looking pattern occurring in nature are, conservatively, about 1 in 50 billion.

The virus did not emerge in Bangkok, Hanoi, Bago, Kunming, Guangdong, or any of the myriad other places with similar animal trade networks and greater contact rates between people and sarbecovirus reservoirs. No. The virus emerged in Wuhan, the exact place and time one would expect from DEFUSE.

With all the evidence pointing the hounds towards NIAID, it is essential for global health security that we further investigate the research NIAID funded in 2019. It is imperative for our constitutional democracy, for our ability to self-govern, that we learn the truth. The only way to learn the truth is to investigate NIAID, the agency Fauci led for 38 years, the agency that funded gain-of-function research of concern, the agency named in the October 2019 call by DEFUSE PI’s, the agency that funded this exact group in 2019.

A preemptive pardon prior to the discovery of truth is a fancy name for obstruction of justice. The Biden administration’s dying breath must be challenged, and we must allow Congress and the incoming administration to investigate the possibility that Anthony Fauci’s NIAID-supported research caused the Covid-19 pandemic.

Republished from the author’s Substack

Author

Alex Washburne is a mathematical biologist and the founder and chief scientist at Selva Analytics. He studies competition in ecological, epidemiological, and economic systems research, with research on covid epidemiology, the economic impacts of pandemic policy, and stock market response to epidemiological news.

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Brownstone Institute

It’s Time to Retire ‘Misinformation’

Published on

From the Brownstone Institute

By  Pierre Kory 

This article was co-authored with Mary Beth Pfieffer.

In a seismic political shift, Republicans have laid claim to an issue that Democrats left in the gutter—the declining health of Americans. True, it took a Democrat with a famous name to ask why so many people are chronically illdisabled, and dying younger than in 47 other countries. But the message resonated with the GOP.

We have a proposal in this unfolding milieu. Let’s have a serious, nuanced discussion. Let’s retire labels that have been weaponized against Robert F. Kennedy, Jr., nominated for Health and Human Services Secretary, and many people like him.

Start with discarding threadbare words like “conspiracy theory,” “anti-vax,” and the ever-changing “misinformation.”

These linguistic sleights of hand have been deployed—by government, media, and vested interests—to dismiss policy critics and thwart debate. If post-election developments tell us anything, it is that such scorn may no longer work for a population skeptical of government overreach.

Although RFK has been lambasted for months in the press, he just scored a 47 percent approval rating in a CBS poll.

Americans are asking: Is RFK on to something?

Perhaps, as he contends, a 1986 law that all but absolved vaccine manufacturers from liability has spawned an industry driven more by profit than protection.

Maybe Americans agree with RFK that the FDA, which gets 69 percent of its budget from pharmaceutical companies, is potentially compromised. Maybe Big Pharma, similarly, gets a free pass from the television news media that it generously supports. The US and New Zealand, incidentally, are the only nations on earth that allow “direct-to-consumer” TV ads.

Finally, just maybe there’s a straight line from this unhealthy alliance to the growing list of 80 childhood shots, inevitably approved after cursory industry studies with no placebo controls. The Hepatitis B vaccine trial, for one, monitored the effects on newborns for just five days. Babies are given three doses of this questionably necessary product—intended to prevent a disease spread through sex and drug use.

Pointing out such conflicts and flaws earns critics a label: “anti-vaxxer.”

Misinformation?

If RFK is accused of being extreme or misdirected, consider the Covid-19 axioms that Americans were told by their government.

The first: The pandemic started in animals in Wuhan, China. To think otherwise, Wikipedia states, is a “conspiracy theory,” fueled by “misplaced suspicion” and “anti-Chinese racism.”

Not so fast. In a new 520-page report, a Congressional subcommittee linked the outbreak to risky US-supported virus research at a Wuhan lab at the pandemic epicenter. After 25 hearings, the subcommittee found no evidence of “natural origin.”

Is the report a slam dunk? Maybe not. But neither is an outright dismissal of a lab leak.

The same goes for other pandemic dogma, including the utility of (ineffective) masks, (harmful) lockdowns, (arbitrary) six-foot spacing, and, most prominently, vaccines that millions were coerced to take and that harmed some.

Americans were told, wrongly, that two shots would prevent Covid and stop the spread. Natural immunity from previous infection was ignored to maximize vaccine uptake.

Yet there was scant scientific support for vaccinating babies with little risk, which few other countries did; pregnant women (whose deaths soared 40 percent after the rollout), and healthy adolescents, including some who suffered a heart injury called myocarditis. The CDC calls the condition “rare;” but a new study found 223 times more cases in 2021 than the average for all vaccines in the previous 30 years.

Truth Muzzled?

Beyond this, pandemic decrees were not open to question. Millions of social media posts were removed at the behest of the White House. The ranks grew both of well-funded fact-checkers and retractions of countervailing science.

The FDA, meantime, created a popular and false storyline that the Nobel Prize-winning early-treatment drug ivermectin was for horses, not people, and might cause coma and death. Under pressure from a federal court, the FDA removed its infamous webpage, but not before it cleared the way for unapproved vaccines, possible under the law only if no alternative was available.

An emergency situation can spawn official missteps. But they become insidious when dissent is suppressed and truth is molded to fit a narrative.

The government’s failures of transparency and oversight are why we are at this juncture today. RFK—should he overcome powerful opposition—may have the last word.

The conversation he proposes won’t mean the end of vaccines or of respect for science. It will mean accountability for what happened in Covid and reform of a dysfunctional system that made it possible.

Republished from RealClearHealth

Author

Dr. Pierre Kory is a Pulmonary and Critical Care Specialist, Teacher/Researcher. He is also the President Emeritus of the non-profit organization Front Line COVID-19 Critical Care Alliance whose mission is to develop the most effective, evidence/expertise-based COVID-19 treatment protocols.

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